Given the complex nature of this subject, it is beyond the scope of this article to provide an in-depth review of all aspects of immunology.

NK cells (also known as large granular lymphocytes [LGLs]) play a major role in the rejection of tumours and the destruction of cells infected by viruses. By using this website, you agree to our Immunology is the study of the immune system, it deals with how the natural body soldiers help to fight and eliminate intruders (microorganisms) that causes diseases in our body.

Both of these cells share a similar function: to engulf (phagocytose) microbes. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Cancer or tumors need to be discussed only in connection with immunology. Each of these antibodies has differing biological functions and recognize and neutralize specific pathogens. This, in turn, attracts the assistance of Th cells which secrete cytokines that help the B cell multiply and mature into antibody-secreting plasma cells. A brief overview of the defining features of innate and adaptive immunity are presented in Table There is a great deal of synergy between the adaptive immune system and its innate counterpart, and defects in either system can lead to immunopathological disorders, including autoimmune diseases, immunodeficiencies and hypersensitivity reactions. Introduction Over the past decade, there have been numerous advances in our current understanding of the immune system and how it functions to protect the body from infection.

Introduction to immunology 1. Saddam AnsariTbilisi State Medical UniversityImmunology 2. Introduction to immunology, Science of Immunity 1. The principal function of B cells is the production of antibodies against foreign antigens [When activated by foreign antigens, B cells undergo proliferation and differentiate into antibody-secreting plasma cells or memory B cells (see Figure Given their function in antibody production, B cells play a major role in the humoral or antibody-mediated immune response (as opposed to the cell-mediated immune response, which is governed primarily by T cells) [Antibody-mediated immunity is the branch of the acquired immune system that is mediated by B-cell antibody production.

Introduction to Immunology Science of Immunity How we are Protected Dr.T.V.Rao MD Dr.T.V.Rao MD 1 2.


Common environmental allergens inducing IgE-mediated allergies include cat-, dog- and horse epithelium, pollen, house dust mites and molds. Table Antibodies play an important role in containing virus proliferation during the acute phase of infection.

Disease-causing antigens are called pathogens. The hallmark of autoimmunity is the presence of self-reactive T cells, auto-antibodies, and inflammation. Follow the link, new dating source: ❤❤❤ http://bit.ly/2u6xbL5 ❤❤❤ The antibody-production pathway begins when the B cell’s antigen-binding receptor recognizes and binds to antigen in its native form.
Your message goes here Adaptive immunity, on the other hand, is antigen-dependent and antigen-specific; it has the capacity for memory, which enables the host to mount a more rapid and efficient immune response upon subsequent exposure to the antigen. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Class I MHC molecules present endogenous (intracellular) peptides while class II molecules present exogenous (extracellular) peptides. Unlike mast cells, which generally reside in the connective tissue surrounding blood vessels, basophils reside in the circulation.

The Th1 response is characterized by the production of interferon-gamma (IFN-γ) which activates the bactericidal activities of macrophages, and other cytokines that induce B cells to make opsonizing (coating) and neutralizing antibodies. The innate immune response has no immunologic memory and, therefore, it is unable to recognize or “memorize” the same pathogen should the body be exposed to it in the future. Unlike T cells, B cells can recognize free antigen directly, without the need for APCs.

J Allergy Clin Immunol.